Friday, 18 May 2007 - 11:30 AM
210 (Pfahler Hall)
415

Toward the total synthesis of ritterazine O

Jean-Michel Joerger and Douglass F. Taber. University of Delaware, Newark, DE

We have prepared the enantiomerically-pure 5/5-spiroketal 2 required for the synthesis of the ritterazines, by ring closure of 1 followed by equilibration with high diastereocontrol. Further, we have coupled the spiroketal with 3, and after a series of transformations, we have obtained 4. We will describe progress toward our target 5.


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