Opioid analgesics are commonly used to treat pain. There is a wide spectrum of pain namely, acute (injury), chronic (back pain), and neuropathic pain (diabetes, cancer, shingles). Non opioid analgesics such as acetaminophen, naproxen and ibuprofen are relatively safe, but lack efficacy for acute, chronic or neuropathic pain. Mu receptor opioids such as morphine, codeine, fentanyl, etc are efficacious but have undesirable side effects including addiction, nausea, constipation and respiratory depression. On the other hand, delta receptor opioids are found to be non-addictive while displaying the same potency as that of mu receptor opioids. We have developed a short and efficient synthesis towards novel delta receptor opioids, which are expected to be non-addictive.