Daniel Mayo1, Melissa Zastrow2, Robin McCann1, and Isabelle Lagadic2. (1) Shippensburg University, Shippensburg, PA, (2) University of Connecticut, Storrs, CT
Non-Steroidal Anti-Inflammatory drugs have been known to have a low solubility in water which causes complications of the drug to disperse. To combat this inevitable concern of low solubility, functionalized HMS can be used to prevent recrystalization. The cytotoxicity of one such functionalized HMS compound (HMS-SO3) was determined in two different cells lines, an intestinal cell line and a kidney cell line. A non-radioactive cell proliferation assay was used to determine a relatively high ED50.
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