Photoswitches based on anthracene, diarylethenes and spiropyranes were synthesized and attached to supramolecular host molecules as calixarenes (1) as well as fluorescence dyes (2). Photoaffinity switching of 1 were studied in solution and on surface by means of AFM. Photochemical and photophysical investigations of 2 show that these compounds efficiently interact with the attached fluorescence dyes in order to achieve photoswitchable fluorescence.