The increasing pace of drug discovery and development in recent years demands 'high throughput' pharmaceutical process research. Chromatography is an increasingly valuable tool for enabling and expediting pharmaceutical process research. In this presentation, a variety of automated tools for chiral and achiral chromatographic method screening and development to support in-process monitoring, high throughput analysis, cGMP release testing, and preparative chromatography will be presented. Topics to be covered include automated SFC and HPLC screening, fast chromatography approaches for high throughput analysis, multiparallel method screening and development using microfluidic HPLC, as well as automated databasing and data mining of chromatographic screening results.