Pesticides are substances which protect plants against molds, fungi, and insects; therefore decreasing the percent of crop loss for harvest and potential illness. Most pesticides are produced by plants naturally to ward off their predators. The amount of man-made pesticides applied and their residue allowed to remain on products at market are regulated and inspected by the U.S. Department of Agriculture, the Environmental Protection Agency and the Food and Drug Administration. The Food and Drug Administration (FDA) has three main objectives in respect to pesticides: 1)to sample and analyze fresh and processed domestic and imported foods for pesticide residues and industrial chemicals; 2) to initiate enforcement action for shipments found to contain illegal residues; 3) to generate information on the incidence and levels of pesticide residues in domestic and imported foods. Sample analysis is performed according to official pesticide methods that published in the FDA Pesticide Analytical Manual (PAM) and other analytical methods published in scientific journals.