The molecular self-assembly of a series of benzene carboxylic acid derivatives has been investigated at the liquid-graphite interface using scanning tunneling microscopy (STM) and computational chemistry methods. The two-dimensional self-assembled networks are stabilized through the formation of multiple, cooperatively strengthened hydrogen bonds. The structure of the monolayers formed on graphite by three different molecules � trimesic acid (1,3,5-benzenetricarboxylic acid), trimellitic acid (1,2,4-benzenetricarboxylic acid), and pyromellitic acid (1,2,4,5-benzenetetracarboxylic acid) � in a series of alkanoic acid and alcohol solvents and solvent mixtures will be described. In conjunction with STM imaging, Density Functional Theory calculations are used to shed light on the structural preferences of isolated analogue molecules and the energetics of conformational change. Solvent induced pseudo-polymorphism is observed in the assembly structures of trimesic acid and pyromellitic acid. Furthermore, the deterministic role played by the solution concentration on network formation will be discussed in light of these and recent literature results.