A semiconductor|electrolyte interface is normally characterized by double layer capacitance leading to reactive impedance. This characteristic is undesirable for bioelectrode design. Since uncompensated charge exists only at the surface in steady-state for conductors, sensing is detrimentally affected, as the reactive impedance creates a high-pass filter intrinsic to series reactances. For this reason, the achievement of an Ohmic interface would be highly desirable. In our laboratory, we have achieved near Ohmic behavior for electrodes in vitro within a broad frequency range when modified with PEDOT film. We have suggested that ohmic behavior is primarily due to the identity of counterion, homogeneity and low porosity of the film. Using Electrochemical Impedance Spectroscopy and Raman Spectroscopy, we have conducted a comparative study of PEDOT and PEDOP based on their chemical identity and we found that the heteroatom may be playing a role in observed ohmic behavior for PEDOT by contributing to the formation of specific chemical states that affect the uncompensated charge at the surface. Results will be reported and discussed for PEDOT and PEDOP.