Heavy metals play a significant negative role in human health and well-being. A variety of these metals are in common exposure and most individuals are unaware of their complications. This discussion will include the most common types, occurrence and medical concerns therein. Substances such as aluminum, arsenic, cadmium, mercury, lead, nickel, and copper are associated with a variety of disorders including Parkinson's Disease, MS, ALS, Alzheimer's Disease, Lupus, cardiovascular compromise including heart failure and cardiomyopathy, immune dysfunction, cancer, and developmental disorders including autism. Abstracts from the medical literature have supported these correlations and will be referenced at the presentation.