Michelle J. Cho, Queensborough Community College - CUNY, Bayside, NY, Gopal Subramaniam, City University of New York, Queens College,, Flushing, NY, Keith Ramig, Baruch College - CUNY, New York, NY, and Sasan Karimi, Queensborough Community College, Bayside, NY.
Benzazepines are a pharmacologically important class of heterocycles. The biological activity of this class of heterocycles gave us the impetus to investigate a generalized approach towards the synthesis of little known 3H-1-benzazepines. To test the generality of the approach, new derivatives of 1-benzazepines containing substituted aryl groups at positions 2 and 4 were synthesized. The orientation of the aryl groups at positions 2 and 4 with respect to the plane of 1-benzazepine ring moiety were examined using various NMR experiments