Sunday, May 18, 2008: 1:30 PM-5:00 PM
Science Building, Rm S-112 (Queensborough Community College)
Process Chemistry
This session will highlight topics pertaining to the synthesis, optimization, purification and isolation of pharmaceutically interesting compounds or intermediates. Emphasis will be on the development and application of novel and practical solutions to challenges incurred during preparation of these materials.
Organizer:Rick Sidler
1:30 PMFrom the Bench to the Plant : Case Studies in the Development and Scale up of Chemical Processes
Akin H. Davulcu
2:00 PMProcess Chemistry Meets RNA: Optimization and Implementation of a Cleavage-Deprotection Strategy for Synthetic Oligonucleotides
Amran Gowani
2:30 PMA Novel and Efficient Cleavage of Silyl Ethers
Daniel Zewge, Rick Sidler, Raymond Cvetovich
3:00 PMDevelopment of a Scaleable Process for Product Quality Improvement Using Adsorbents
Melodie D. McCain, Jungchul Kim, Jennifer Vance, Thomas Hunter
3:30 PMBreak
3:45 PMRecent Advances in the Use of Preparative Chromatography in the Multikilogram Synthesis of Preclinical Pharmaceutical Candidates
Derek Henderson
4:15 PMHighly Active, Air-Stable Supported and Unsupported Homogeneous Catalysts for Challenging Coupling Reactions in Pharmaceutical Process
Thomas Colacot

Back to The 40th Middle Atlantic Regional Meeting (MARM) (May 17�21, 2008)