Wednesday, 16 May 2007: 1:50 PM-5:00 PM | |||
208 (Pfahler Hall) | |||
Carbohydrate Chemistry/Glycoprotein | |||
This session will be dealing with the latest data on studies of the biochemical roles of glycoproteins and glycosylation enzyme mechanisms. Multiple important therapeutic applications are currently indicated with the use of carbohydrate chemistry including chemo-enzymatic synthesis of novel synthetic carbohydrates and enzyme replacement therapy. The speakers will present their work on such �hot� topics as: development of conjugate vaccines from synthetic carbohydrate antigens, methods of preparation of neoglycoconjugates, progress in studies of mechanisms of Hepatitis B virus and the role of N-glycosylation and glycan processing in the secretion of the viral particles, synthesis and immunological studies of oligomannose-containing glycoconugates in the course of developing carbohydrate-based HIV-1 vaccines, conformation and dynamics of complex polysaccharides and oligosaccharides from pathogenic bacteria, the role of carbohydrates as recognition molecules in biological systems, and their industrial applications. | |||
Organizers: | Larisa Toulokhonova Sami Saribas | ||
Presider: | Sami Saribas | ||
1:50 PM | 123 | Glycoproteomics of the early detection and management of chronic viral disease Timothy Block | |
2:10 PM | 124 | Production and biological activity of gangliosides Shawn DeFrees | |
2:30 PM | 125 | Neoglycoconjugates from the synthetic tetrasaccharide side chain of the Bacillus anthracis exosporium Pavol Kovac, Rina Saksena, Roberto Adamo | |
3:10 PM | 126 | Chemoenzymatic synthesis of homogeneous glycoproteins Lai-Xi Wang | |
3:30 PM | Break | ||
3:40 PM | 127 | Engineering the Cell Wall Receptor Polysaccharides of Oral Streptococci and their Structures by NMR Spectroscopy C. Allen Bush, Yasuo Yoshida, Soumya Ganguly, John O. Cisar | |
4:00 PM | 128 | Structure and function of glycosyltransferases and structure-based design of novel glycosyltransferases Pradman K. Oasba | |
4:20 PM | 129 | Syntheses of unnatural glycoconjugates with vast biological applications Maria R. Manzoni, Boopathy Ramakrishnan, Elizabeth Boeggeman, Pradman K. Qasba | |
4:40 PM | 130 | Tautomeric Modification of GlcNAc-Thiazoline Kehinde A. Ajayi, Mohannad Abdo, Spencer Knapp |
Back to The Middle Atlantic Regional Meeting (May 16 - 18, 2007)