Wednesday, 16 May 2007: 1:50 PM-5:00 PM
208 (Pfahler Hall)
Carbohydrate Chemistry/Glycoprotein
This session will be dealing with the latest data on studies of the biochemical roles of glycoproteins and glycosylation enzyme mechanisms. Multiple important therapeutic applications are currently indicated with the use of carbohydrate chemistry including chemo-enzymatic synthesis of novel synthetic carbohydrates and enzyme replacement therapy. The speakers will present their work on such �hot� topics as: development of conjugate vaccines from synthetic carbohydrate antigens, methods of preparation of neoglycoconjugates, progress in studies of mechanisms of Hepatitis B virus and the role of N-glycosylation and glycan processing in the secretion of the viral particles, synthesis and immunological studies of oligomannose-containing glycoconugates in the course of developing carbohydrate-based HIV-1 vaccines, conformation and dynamics of complex polysaccharides and oligosaccharides from pathogenic bacteria, the role of carbohydrates as recognition molecules in biological systems, and their industrial applications.
Organizers:Larisa Toulokhonova
Sami Saribas
Presider:Sami Saribas
1:50 PMGlycoproteomics of the early detection and management of chronic viral disease
Timothy Block
2:10 PMProduction and biological activity of gangliosides
Shawn DeFrees
2:30 PMNeoglycoconjugates from the synthetic tetrasaccharide side chain of the Bacillus anthracis exosporium
Pavol Kovac, Rina Saksena, Roberto Adamo
3:10 PMChemoenzymatic synthesis of homogeneous glycoproteins
Lai-Xi Wang
3:30 PMBreak
3:40 PMEngineering the Cell Wall Receptor Polysaccharides of Oral Streptococci and their Structures by NMR Spectroscopy
C. Allen Bush, Yasuo Yoshida, Soumya Ganguly, John O. Cisar
4:00 PMStructure and function of glycosyltransferases and structure-based design of novel glycosyltransferases
Pradman K. Oasba
4:20 PMSyntheses of unnatural glycoconjugates with vast biological applications
Maria R. Manzoni, Boopathy Ramakrishnan, Elizabeth Boeggeman, Pradman K. Qasba
4:40 PMTautomeric Modification of GlcNAc-Thiazoline
Kehinde A. Ajayi, Mohannad Abdo, Spencer Knapp

Back to The Middle Atlantic Regional Meeting (May 16 - 18, 2007)