We have developed a lecture and laboratory course for non-science majors at NYU that teaches chemical principles through the context of biological molecules. This approach reflects the current trend in scientific research where chemistry and biology meet at the interface of “chemical biology.” Whenever possible, the course uses current issues to engage students with learning chemistry – for example, our section on organic chemistry begins with a consideration of “trans fats.” This presentation will describe the educational goals of the course and the preliminary results of assessment tests of student learning in the areas of three-dimensional visualization and drug development. This project is supported by NSF grant 043014 from the Division of Undergraduate Education.